In this video, Dr. Katz and Dr. Gildea highlight how glyphosate turns off your body's ability to detox and why BrocElite is the antidote to this dangerous toxin.
Listen time: 6 minutes
Martin Katz (00.09):
Hi, I'm Martin Katz, MD. Double board certified in sports medicine and family medicine, but my true love is prevention and getting people really interested in health. I'm joined by John Gildea, research scientist, studied at Johns Hopkins, and together we make a great team, an MD-PhD. We're the founders of BrocElite, the natural form of sulforaphane. It's stabilized, thanks to John.
Martin Katz (00.35):
And today we're going to talk a little bit about glyphosate, this molecule that was derived to possibly make our food system better. But the question is, has it? And we would argue, certainly not. And the reason for that is, glyphosate affects a pathway that affects plants and microorganisms, and we're now realizing the importance, certainly, of plants and the way they're naturally derived, and microorganisms on our skin and our gut, and how important they are to our health.
Martin Katz (01.10):
And the problem with glyphosate, now, is we're finding it everywhere. It's sprayed on foods, especially soy, canola, even beets, certain fruits, and it's in our waterways when they're spraying it. It's in the air. So it's really quite ubiquitous. It's everywhere. And the problem with that is, it's now affecting the soil that plants are grown in. It's affecting the plants around those crops and it's affecting our health, and studies are certainly starting to show that, certainly in cows, rats, and humans. And now these companies are actually under fire for showing detriment to our health. It also infects our reproduction system.
Martin Katz (01.57):
But we want to sort of explore what our product has shown with glyphosate, and what's called the Nrf2 pathway. And this pathway, and John's going to talk about this in a second, is an incredibly important pathway. This Nrf2 pathway, basically, if you knock it out, you're not surviving. It's incredibly important with regard to decreasing oxidative stress, which is where your body can create inflammation, if it's out of control. And it also decreases toxins. And that's important because, going back to glyphosate, glyphosate actually knocks down this Nrf2, so it's making all toxins more toxic. And so you're really struggling now with Nrf2, especially where we found, where glyphosate decreases Nrf2 to the point it's dysfunctional or even nonfunctional. So, John, what did we find?
John Gildea (02.53):
Yeah, so glyphosate can be used in cell culture models, and one of the models out there is a cell culture model of liver cells called hepatocytes, and they do the bulk of the detoxification in your body. It's called first-pass metabolism. So it does a lot of the detoxification in your body. So we took those cells and put a dose of glyphosate on them and showed that it reduces Nrf2. And so it made sense that we showed that it went down, but no need telling a bad story unless you have the antidote. And in this case, Nrf2 going down was completely blocked by sulforaphane in a dose that you can get in the human body. So we tried to match the dose as well.
John Gildea (03.43):
And so stabilized sulforaphane in BrocElite was able to raise the Nrf2 levels. Glyphosate reduced it, but if you put them both together, came back to completely normal, so we have the answer to the dilemma there. And it's really important in that I'm not sure people really understand this idea of selection. In biology, you're doing a lot of things where you have a selection agent. In this case, if you think of glyphosate as the selection agent, the basis of this system in our food system is that, in the plant that you're trying to grow, a crop, you put the resistance gene into that plant. So you have a selection agent, and then you have the resistance gene. And of course, you would think, okay, the corn or whatever the genetically modified plant is, will be just fine. Yes, it survives, it doesn't get killed, but even in the plant that is being selected, it's not completely normal. It's affecting the bacteria that are around the plants and everything else.
John Gildea (04.53):
So in a simple analogy, I like to think about that the genetically modified plant is the only organism on Earth that's not affected by glyphosate. Everyone else is. And that's a real dilemma, because you can't even do studies. How can you do a study when glyphosate is in everything? You can't even do a scientific study on it. Is it a, you compare people that only drink their own water and live off the land completely? There's not very many nomadic tribes around where you could get the correct controls. But anyway, that's how I think of glyphosate, and the antidote is a really important one.
Martin Katz (05.36):
Yeah. That's, again, a bright spot. And part of the reason that we want to bring you these products is to create health, certainly in our families and yours. And so, please click on the link below to read more. This is a very important discussion, a very important topic point. We'll continue to bring you more, but thanks for listening.