Glycine and NAC: An Age Reversing Strategy

 I recently came across a study published in January 2023, where researchers from Baylor performed a double-blind, placebo-controlled, randomized control trial looking at how mega doses of glycine and N-acetyl cysteine (NAC) improve age-related biomarkers. It’s a follow-up study from 2021 that I’ve talked about. 

In the study, the researchers looked at 24 older participants between 61 and 80 years, with a mean age of 71 years. Half took 8 grams of glycine and 8 grams of NAC (GlyNAC), while the other half (controls) were given 16 grams of alanine for 12 weeks.

With elevated oxidative stress and mitochondrial dysfunction identified as key hallmarks of aging, improving and reversing these defects in older adults is a goal of this study.  Oxidative stress is a harmful condition caused by an imbalance between free radicals and antioxidants.  Mitochondria are the energy-producing structures in cells, and their dysfunction is linked to aging.  Along with these, glutathione is a potent antioxidant that decreases with age.

With NAC and glycine being building blocks of glutathione, it’s not surprising that this combination improved and reversed multiple age-associated abnormalities including mitochondrial health, blood pressure, waist circumference and telomere health.

I’ve been taking this for 1.5 weeks and noticed improvements in blood pressure and muscle pain.  One I reach 12 weeks, I’ll give you annother update!