The Best Supplement Delivering Bioavailable Berberine That Your Body Can Absorb

Lowers Blood Sugar

Berberine (BBR) has been shown in clinical trials to reduce fasting blood glucose (FBG) by 35% and hemoglobin A1c (HbA1c) by 21% over 3 months and 21% (FBG) and 12% (HbA1c) over 2 weeks. 1 2 These results are largely due to BBR blocking gluconeogenesis (turning protein into glucose) in the liver.³

BBR is extremely hard to get into the body (only 0.3% gets in). The unique BerbElite™ formula allows for more BBR to be absorbed through the intestinal barrier.

Promotes Sleep & Mood

Berberine (BBR) has been shown to have a therapeutic effect on insomnia. When compared to diazepam (Valium), BBR alleviated insomnia more quickly while also providing an overall health benefit. BBR has also been shown to dramatically increase serotonin (47%) and dopamine (31%) with short-term use. BBR also improves sleep by lowering blood glucose. This is because increase in melatonin levels at night leads to a decrease in insulin levels in the blood. If you go to bed with high blood glucose, this insulin depression means that your body cannot process the glucose. High blood glucose is known to negatively impact sleep. ⁶

Protects Brain Function

Berberine (BBR) turns on enzymes that protect brain cells, even in low oxygen environments where these cells usually die. BBR also inhibits neuroinflammation in the brain by regulating the HO-1 pathway. The unique combination of BBR and sulforaphane in BerbElite™ turns on the Nrf-2 pathway to protect against oxidative damage in the brain and keeps it the Nrf-2 in the nucleus longer by slowing its exit. Low Nrf-2 functioning is linked to neurodegenerative diseases like Parkinson’s and Alzheimer’s.

When BBR is bioavailable, it lowers blood glucose quickly by increasing AMP kinase production which promotes the transport of glucose from blood to muscle cells.^{10 11}

Blocks c-Myc

Perhaps the most impressive but least appreciated benefit of berberine (BBR) is that it is the only natural supplement that inhibits c-Myc. C-Myc is a transcription factor that, when turned on can create some negative health consequences that we cannot describe here due to FDA regulations. However, go to pubmed.gov and type in “berberine” and “c-myc” to learn more.

Promotes Gut Health

Plants containing berberine (BBR) have been traditional remedies for diarrhea in Chinese and Indian medicine for thousands of years. BBR has been shown to stop leak gut that causes food sensitivities by closing intestinal barrier known as tight junctions. BBR improves the gut microbiome by increasing the number of butyrate producing bacteria.^{13 14 15 16}